NASAL CORTICOSTEROID SPRAYS: USE, CONTRAINDICATIONS AND SIDE EFFECTS

Posted on 26th December 2010 by admin in Allergies
Uses For Nasal Corticosteroid Sprays
Nasal conditions in which nasal corticosteroid sprays are indicated include the following:
- Seasonal allergic rhinitis
- Perennial allergic rhinitis
- Non-allergic rhinitis (vasomotor)
- Nasal polyps (prevent recurrence of polyps following surgical removal)
- Chemical rhinitis (the nose-drop or nose spray nose)
Contraindications For Corticosteroid Nasal Spray
There are two general contraindications to the use of corticosteroid nasal sprays:
1. An allergic or hypersensitivity reaction to either the corticosteroid or one of the additives in the spray you plan to use, manifested by sneezing, congestion, generalized itching, coughing, wheezing, fainting, etc.
2. An untreated but significant infection of the lining membrane of the nose.
NOTE: If you are having pain in your nose and/or blowing copious amounts of pus, perhaps with blood intermixed, from your nose, talk to your doctor before you use one of these sprays.
Side Effects Of Corticosteroid Nasal Sprays
The side effects of corticosteroid nasal sprays are generally mild and limited to the nose. Systemic side effects are possible at higher-than-recommended doses.
Common side effects include burning, stinging, and irritation of the lining of the nose.
Less common side effects include aggravation of bronchial asthma (by accidentally inhaling the solution into the lungs during spraying), headache, light headedness, nausea, nose bleeding, and rebound nasal congestion (if your nasal congestion worsens with use rather than improves). Rare but possible side effects include a decrease in function of the adrenal glands, allergy to the product or an additive, glaucoma (alert doctor if you have a family history of glaucoma), injury of the nasal septum (the wall that divides the nose into right/left sides), sore throat, thrush, and watering of the eyes.
*48/322/5*

NASAL CORTICOSTEROID SPRAYS: USE, CONTRAINDICATIONS AND SIDE EFFECTSUses For Nasal Corticosteroid SpraysNasal conditions in which nasal corticosteroid sprays are indicated include the following:- Seasonal allergic rhinitis- Perennial allergic rhinitis- Non-allergic rhinitis (vasomotor)- Nasal polyps (prevent recurrence of polyps following surgical removal)- Chemical rhinitis (the nose-drop or nose spray nose)
Contraindications For Corticosteroid Nasal SprayThere are two general contraindications to the use of corticosteroid nasal sprays:1. An allergic or hypersensitivity reaction to either the corticosteroid or one of the additives in the spray you plan to use, manifested by sneezing, congestion, generalized itching, coughing, wheezing, fainting, etc.2. An untreated but significant infection of the lining membrane of the nose.NOTE: If you are having pain in your nose and/or blowing copious amounts of pus, perhaps with blood intermixed, from your nose, talk to your doctor before you use one of these sprays.
Side Effects Of Corticosteroid Nasal SpraysThe side effects of corticosteroid nasal sprays are generally mild and limited to the nose. Systemic side effects are possible at higher-than-recommended doses.Common side effects include burning, stinging, and irritation of the lining of the nose.Less common side effects include aggravation of bronchial asthma (by accidentally inhaling the solution into the lungs during spraying), headache, light headedness, nausea, nose bleeding, and rebound nasal congestion (if your nasal congestion worsens with use rather than improves). Rare but possible side effects include a decrease in function of the adrenal glands, allergy to the product or an additive, glaucoma (alert doctor if you have a family history of glaucoma), injury of the nasal septum (the wall that divides the nose into right/left sides), sore throat, thrush, and watering of the eyes.*48/322/5*

HIV: CAUSES OF CONSTITUTIONAL SYMPTOMS-DRUGS AND HIV INFECTION

Posted on 18th December 2010 by admin in HIV
Constitutional symptoms can also be caused by drugs. People with HIV infection take many drugs either to treat or to prevent infections, and to treat anxiety, depression, fever, aches, and problems with sleep and appetite. Many of these drugs have side effects, ranging in seriousness from drowsiness (from antihistamines) to kidney damage and anemia (from amphotericin B). The only side effects of many drugs are constitutional symptoms, particularly fever and rash.
For reasons that are unclear, side effects are more common in people with HIV infection. For instance, trimethoprim—sulfamethoxazole (Bactrim or Septra) causes side effects in 10 percent of the people without HIV infection and 50 percent of those with HIV infection.
Finding out which drugs are causing side effects and stopping the side effects requires the advice of a physician. The physician will either advise what is called a drug
holiday—discontinuation of all drugs—or will stop drugs one at a time.
HIV infection-Some people have constitutional symptoms that cannot be attributed to an opportunistic infection or an opportunistic tumor, or to the side effects of drugs. In such cases, HIV itself might be responsible.
Constitutional symptoms with no causes other than HIV usually occur late in the course of the infection. The treatment is drugs directed at HIV—like AZT—or drugs that simply relieve the constitutional symptoms—aspirin, acetaminophen, ibuprofen, or similar drugs. These drugs are often given on a trial basis, in varying combinations and increasing doses.
*143\191\2*

HIV: CAUSES OF CONSTITUTIONAL SYMPTOMS-DRUGS AND HIV INFECTIONConstitutional symptoms can also be caused by drugs. People with HIV infection take many drugs either to treat or to prevent infections, and to treat anxiety, depression, fever, aches, and problems with sleep and appetite. Many of these drugs have side effects, ranging in seriousness from drowsiness (from antihistamines) to kidney damage and anemia (from amphotericin B). The only side effects of many drugs are constitutional symptoms, particularly fever and rash.     For reasons that are unclear, side effects are more common in people with HIV infection. For instance, trimethoprim—sulfamethoxazole (Bactrim or Septra) causes side effects in 10 percent of the people without HIV infection and 50 percent of those with HIV infection.     Finding out which drugs are causing side effects and stopping the side effects requires the advice of a physician. The physician will either advise what is called a drug holiday—discontinuation of all drugs—or will stop drugs one at a time.     HIV infection-Some people have constitutional symptoms that cannot be attributed to an opportunistic infection or an opportunistic tumor, or to the side effects of drugs. In such cases, HIV itself might be responsible.      Constitutional symptoms with no causes other than HIV usually occur late in the course of the infection. The treatment is drugs directed at HIV—like AZT—or drugs that simply relieve the constitutional symptoms—aspirin, acetaminophen, ibuprofen, or similar drugs. These drugs are often given on a trial basis, in varying combinations and increasing doses.*143\191\2*

BIO-DIVERSITY: GENETIC DIVERSITY

Posted on 12th December 2010 by admin in Herbal
The loss of genetic diversity of the world’s food plants is an issue of serious concern with implication for the long term maintenance of global food supplies. This diversity is rapidly disappearing at a line when more genetic diversity is needed in crop breeding programmes to increase food production.
The extent of genetic erosion differ for various crops and for such erosion number of factors are responsible.
To quote few examples:
The loss of local land races for Rice, Wheat and Maize has been a serious problem in various parts of the world.
The introduction of new high yielding varieties of wheat has caused severe genetic erosion in Turkey, Iraq, Afghanistan, Pakistan and India.
90% of the native varieties of wheat have been lost in 40 years in Greece.
Some of the most valuable commercial species, particularly timber species in Ghana have suffered genetic erosion because of heavy exploitation and they are threatened with extinction in their areas of natural distribution.
For the international market Rattan’s (Lionoid palms) provide the second most important source of export earning from tropical forests of south and south-east Asia. Rattans are mainly used in the production of cane furniture for international market whereas for local uses it is used for production of mats, baskets, fish traps dyes & medicines.
Heavy exploitation combined with habitat destruction has led to the decline of major commercial Rattan species.
Medicinal plants species, to a large extent are harvested from the wild and relatively few are cultivated as crop plants. Out of total 21,000 plants tested by World Health Organisation (WHO) as medicinally important, about 5,000 higher plant mostly temperate species have been thoroughly investigated as potential sources of new drugs. However, biochemical potential of tropical plants has been largely overlooked. Nevertheless around 80% of people in developing countries rely on the traditional medicines. Over exploitation of medicinal plants extracted from the wild flora is leading to problems of genetic erosion in some of the regions. For example, in India where 2,500 plant species are used by traditional healers, some of the medicinal plants (species of Rauwolfia, Aconitum, Dioscorea & Ephedra) are under threat.
Ornamental plants are important commodity in international trade. Today, the diversity of decorative plant species established in cultivation surpasses the variety of plants commonly grown for food around the world. Total world import of cut flowers, foliage and plants amounted to Rs. 2,488 million in 1985 as compared to food, fruit and forage crops. Now, priority both nationally and internationally is given for the conservation of these genetic resources of such ornamental plants, inspite of their such economic potential.
In international trade nearly five million plants belonging to 5,000 orchid species have been recorded in CITES. Thailand is a major country for Orchids in international trade, and Dendrobium is the most heavily traded orchid genus exported. In Japan, out of 70 orchid taxa enlisted in the Japanese Red data book 50 are threatened by over collection. Orchid collection together with habitat destruction has led to the decline of wild orchid species in many other countries.
Cacti and other succulent plants including species of Aloe, Euphorbia and Pachypodium are also traded internationally. The Netherlands, Mexico, and Madagascar are the main source countries which have exported Cacti and succulent plants. This trade poses a severe threat to such plants species.
*17\218\2*

BIO-DIVERSITY: GENETIC DIVERSITY
The loss of genetic diversity of the world’s food plants is an issue of serious concern with implication for the long term maintenance of global food supplies. This diversity is rapidly disappearing at a line when more genetic diversity is needed in crop breeding programmes to increase food production.
The extent of genetic erosion differ for various crops and for such erosion number of factors are responsible.
To quote few examples:The loss of local land races for Rice, Wheat and Maize has been a serious problem in various parts of the world.The introduction of new high yielding varieties of wheat has caused severe genetic erosion in Turkey, Iraq, Afghanistan, Pakistan and India.90% of the native varieties of wheat have been lost in 40 years in Greece.Some of the most valuable commercial species, particularly timber species in Ghana have suffered genetic erosion because of heavy exploitation and they are threatened with extinction in their areas of natural distribution.For the international market Rattan’s (Lionoid palms) provide the second most important source of export earning from tropical forests of south and south-east Asia. Rattans are mainly used in the production of cane furniture for international market whereas for local uses it is used for production of mats, baskets, fish traps dyes & medicines.
Heavy exploitation combined with habitat destruction has led to the decline of major commercial Rattan species.Medicinal plants species, to a large extent are harvested from the wild and relatively few are cultivated as crop plants. Out of total 21,000 plants tested by World Health Organisation (WHO) as medicinally important, about 5,000 higher plant mostly temperate species have been thoroughly investigated as potential sources of new drugs. However, biochemical potential of tropical plants has been largely overlooked. Nevertheless around 80% of people in developing countries rely on the traditional medicines. Over exploitation of medicinal plants extracted from the wild flora is leading to problems of genetic erosion in some of the regions. For example, in India where 2,500 plant species are used by traditional healers, some of the medicinal plants (species of Rauwolfia, Aconitum, Dioscorea & Ephedra) are under threat.Ornamental plants are important commodity in international trade. Today, the diversity of decorative plant species established in cultivation surpasses the variety of plants commonly grown for food around the world. Total world import of cut flowers, foliage and plants amounted to Rs. 2,488 million in 1985 as compared to food, fruit and forage crops. Now, priority both nationally and internationally is given for the conservation of these genetic resources of such ornamental plants, inspite of their such economic potential.In international trade nearly five million plants belonging to 5,000 orchid species have been recorded in CITES. Thailand is a major country for Orchids in international trade, and Dendrobium is the most heavily traded orchid genus exported. In Japan, out of 70 orchid taxa enlisted in the Japanese Red data book 50 are threatened by over collection. Orchid collection together with habitat destruction has led to the decline of wild orchid species in many other countries.Cacti and other succulent plants including species of Aloe, Euphorbia and Pachypodium are also traded internationally. The Netherlands, Mexico, and Madagascar are the main source countries which have exported Cacti and succulent plants. This trade poses a severe threat to such plants species.*17\218\2*

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